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Despite the relative ease that things seem to pierce it, our skin actually does a pretty good job of keeping foreign materials out, especially on the molecular level. In fact, sometimes it does this job too well, making it particularly difficult for scientists to target skinborne ailments. A breakthrough technique from Northwestern University could make fighting some major skin cancers as easy as smearing on moisturizer. The development has created a new way of delivering gene-targeting drugs to the system via epidermal penetration. It a nanostructure that unique in its spherical shape and densely packed nucleic acids. Small interfering RNA siRNA surrounds a gold nanoparticle in a t stanley cup ight sphere, uniquely able t stanley cup o penetrate the epidermis. The structures RNA is then programmed to target specific disease causing genes, potentially like those behind melanoma and squamous cell carcinoma or psoriasis. The nanoparticles were able to be combined with commercial moisturizer, and was able to effectively deeply penetrate both mouse and human skin, with the cells taking up 100% of the drug. The first round of gene therapy was aimed at epidermal growth factor receptor EGFR , a biomarker linked to a number of cancers. In human skin equivalent, the EGFR expression dropped by 52% from 60 hours of treatment, without any signs of toxicity. H stanley cup website opefully that means that in years to come, you ;ll be able to load up your Nivea with a nanoparticle designed to stop skin cancer Jvxg Can an Algorithm Really Predict If a Movie Will Be a Hit
A woman has been arrested by airport police carrying almost three pounds of cocaine in her breasts. Not in her bra, no鈥攊nside her breasts. You can see the cocaine implants in this image. They are 1.5 pounds each. The woman was traveling from Bogot谩, Colombia, to El Prat airport, in Barcelona, Spain. The police thought she was suspicious when she failed to convincingly answer questions at the border control. A female agent took her to a room for a strip search. At that point, she noticed some bloody bandages under her breasts. When stanley cup asked about them, the woman said she just had pl stanley vaso astic surgery to enlarge her breasts. Not convinced, the agent removed the bandages and saw that there were no stitches, just two open wounds on each breast. The bags you see here were clearly visible from the outside, through the op vaso stanley en skin and flesh. She was then immediately transferred to a nearby hospital, where the two plastic bags were removed, containing 3 pounds 1.337 kilograms of pure cocaine. [El Mundo In Spanish ] Welcome to Gizmodo winter break! We ;re exploring the crazier side of tech this month, so check out gizmodo/core if all you want is straight tech news. CrimeDrugsSmuggling
Despite the relative ease that things seem to pierce it, our skin actually does a pretty good job of keeping foreign materials out, especially on the molecular level. In fact, sometimes it does this job too well, making it particularly difficult for scientists to target skinborne ailments. A breakthrough technique from Northwestern University could make fighting some major skin cancers as easy as smearing on moisturizer. The development has created a new way of delivering gene-targeting drugs to the system via epidermal penetration. It a nanostructure that unique in its spherical shape and densely packed nucleic acids. Small interfering RNA siRNA surrounds a gold nanoparticle in a t stanley cup ight sphere, uniquely able t stanley cup o penetrate the epidermis. The structures RNA is then programmed to target specific disease causing genes, potentially like those behind melanoma and squamous cell carcinoma or psoriasis. The nanoparticles were able to be combined with commercial moisturizer, and was able to effectively deeply penetrate both mouse and human skin, with the cells taking up 100% of the drug. The first round of gene therapy was aimed at epidermal growth factor receptor EGFR , a biomarker linked to a number of cancers. In human skin equivalent, the EGFR expression dropped by 52% from 60 hours of treatment, without any signs of toxicity. H stanley cup website opefully that means that in years to come, you ;ll be able to load up your Nivea with a nanoparticle designed to stop skin cancer Jvxg Can an Algorithm Really Predict If a Movie Will Be a Hit
A woman has been arrested by airport police carrying almost three pounds of cocaine in her breasts. Not in her bra, no鈥攊nside her breasts. You can see the cocaine implants in this image. They are 1.5 pounds each. The woman was traveling from Bogot谩, Colombia, to El Prat airport, in Barcelona, Spain. The police thought she was suspicious when she failed to convincingly answer questions at the border control. A female agent took her to a room for a strip search. At that point, she noticed some bloody bandages under her breasts. When stanley cup asked about them, the woman said she just had pl stanley vaso astic surgery to enlarge her breasts. Not convinced, the agent removed the bandages and saw that there were no stitches, just two open wounds on each breast. The bags you see here were clearly visible from the outside, through the op vaso stanley en skin and flesh. She was then immediately transferred to a nearby hospital, where the two plastic bags were removed, containing 3 pounds 1.337 kilograms of pure cocaine. [El Mundo In Spanish ] Welcome to Gizmodo winter break! We ;re exploring the crazier side of tech this month, so check out gizmodo/core if all you want is straight tech news. CrimeDrugsSmuggling
